Abstract: Objective: Systemic sclerosis is a generalized disorder of connective tissue disease. This study surveyed the clinical manifestations of systemic sclerosis in early (6 years) phases of limited and diffuse variants. Methods: Nineteen patients with diffuse and thirty-four cases with limited form of disease were selected consecutively from 1992 to 1998. Sixty-five clinical data were evaluated and then analyzed by MC-Nemar chi square test between two forms in both phases. Results: (1) There were ...